Conversos and Moriscos in Late Medieval Spain and Beyond, by Kevin Ingram

By Kevin Ingram

Converso and Morisco are the phrases utilized to these Jews and Muslims who switched over to Christianity in huge numbers and customarily below duress in overdue medieval Spain. The Converso and Morisco Studies courses will research the results of those mass conversions for the converts themselves, for his or her heirs (also often called Conversos and Moriscos) and for medieval and sleek Spanish tradition. because the essays during this first quantity attest, the learn of the Converso and Morisco phenomena is not just vital for these students curious about Spanish society and tradition, yet for lecturers in all places drawn to the problems of identification, Otherness, nationalism, spiritual intolerance and the demanding situations of modernity. individuals are Michel Boeglin, William Childers, Barbara Fuchs, Mercedes Garcia-Arenal, Juan Gil, Luis M. Giron-Negron, Kevin Ingram, Francisco Marquez Villanueva, Mark D. Meyerson, Vincent Parello, Francisco Pena Fernandez, Fernando Rodriguez Mediano, Elaine Wertheimer, Nadia Zeldes, and Leonor Zozaya Montes."

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Privileged Scaffolds in Medicinal Chemistry: Design, by Stefan Bräse, David Thurston, Ana Martinez, Dorota

By Stefan Bräse, David Thurston, Ana Martinez, Dorota Jakubczyk, Roland Pfau, Arantxa Encinas, Esther Rösch, Carmen Gil, Kye Masters, Franziska Gläser, Carsten S. Kramer, David Newman, Frederico Albericio, Henning Steinhagen, Lucija Peterlin Masic, Shahriar

One technique to expedite the invention of latest medications, a procedure that's just a little sluggish and serendipitous, is the identity and use of privileged scaffolds. This booklet covers the historical past of the invention and use of privileged scaffolds and addresses a few of the periods of those very important molecular fragments.
The first of the benzodiazepines, a category of gear that's strong for treating anxiousness, would possibly not were came upon had it no longer been for an opportunity scan at the contents of a discarded flask came upon in the course of a lab clean-up. a few years later, scientists found that benzodiazepine derivatives have been additionally potent in treating different illnesses. This category of molecules was once the 1st to be defined as privileged within the experience that it's particularly powerful at changing the process disorder. different privileged molecular constructions have seeing that been came across, and because those compounds are so powerful at interacting with various periods of proteins, they are a good place to begin to seem for brand new medications opposed to the supposedly “undruggable” proteins.
Following introductory chapters offering an summary, a historic standpoint and the theoretical history and findings, major chapters describe the constitution of privileged buildings in flip and speak about significant drug periods linked to them and their syntheses. This e-book offers complete insurance of the topic via chapters contributed by means of professional authors from either academia and and may be a very good reference resource for medicinal chemists of more than a few disciplines and experiences.

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Leaders and Health Care Organizational Change: Art, Politics by Stewart Gabel

By Stewart Gabel

Health and psychological well-being corporations are present process significant adjustments in rules, systems, buildings, and emphasis. a lot of those adjustments seem relating to what should be termed the controlled care revolution. This upheaval in supply structures on the topic of overall healthiness and psychological overall healthiness care has been linked to nice adjustments and swift turnover in leaders and in management positions. it seems that many leaders cannot lead their firms into this or different new territories.
the aim of this e-book is to explain levels that businesses struggle through as they stream swiftly to evolve to new and infrequently undesirable adjustments. The emphasis is at the features of leaders and of management that seem tied to profitable or unsuccessful results for firms in the middle of those fast alterations. specific demanding situations and expectancies which are prone to be found in enterprises and in members dealing with swap are defined. equipment are awarded that will be hired through leaders to confront quite a few problems to be able to direct profitable results for themselves, as leaders, and for his or her corporations. during the ebook, the fundamental and occasionally differing targets of leaders as members and of management as a certified method are highlighted.
This e-book should be of curiosity to leaders and bosses in any respect degrees in numerous future health and psychological future health care organisations, in addition to graduate scholars in wellbeing and fitness care administration, wellbeing and fitness care companies, future health care management, and enterprise management. it is going to even be of curiosity to psychological wellbeing and fitness execs and graduate scholars in business and organizational psychology.

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High-Dimensional Single Cell Analysis: Mass Cytometry, by Harris G. Fienberg, Garry P. Nolan

By Harris G. Fienberg, Garry P. Nolan

This quantity highlights the main fascinating biomedical and medical functions of high-dimensional move and mass cytometry. It stories present sensible ways used to accomplish high-dimensional experiments and addresses key bioinformatic options for the research of information units related to dozens of parameters in thousands of unmarried cells. subject matters comprise unmarried phone melanoma biology; reviews of the human immunome; exploration of immunological phone varieties similar to CD8+ T cells; decipherment of signaling procedures of melanoma; mass-tag mobile barcoding; research of protein interactions by means of proximity ligation assays; Cytobank, a platform for the research of cytometry information; computational research of high-dimensional circulation cytometric information; computational deconvolution methods for the outline of intracellular signaling dynamics and hyperspectral cytometry. All 10 chapters of this ebook were written by means of revered specialists of their fields. it's a useful reference booklet for either simple and medical researchers.

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OCT in Central Nervous System Diseases: The Eye as a Window by Andrzej Grzybowski, Piero Barboni

By Andrzej Grzybowski, Piero Barboni

This e-book stories fresh very important advances within the use of optical coherence tomography (OCT) which will examine neurodegeneration in the retina during the quantification of axonal loss. distinct details is supplied at the function of OCT as a promising device for the assessment of illness development in several neurodegenerative problems and as a organic marker of neuroaxonal harm. The issues thought of contain a number of sclerosis, Parkinson’s sickness, Alzheimer’s ailment, intracranial high blood pressure, Friedreich’s ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia. person chapters also are dedicated to OCT procedure, new OCT expertise in neuro-ophthalmology, OCT and pharmacological therapy, and using OCT in animal types. by way of documenting the power of OCT to supply key details on CNS illnesses, this e-book illustrates convincingly that the attention is certainly the “window to the brain”.

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Biology of Life. Biochemistry, Physiology and Philosophy by Laurence A. Cole

By Laurence A. Cole

Biology of existence: Biochemistry, body structure and Philosophy offers foundational insurance of the sphere of biochemistry for a unique attitude to the normal biochemistry textual content by way of concentrating on human biochemistry and incorporating similar components of evolution to aid extra contextualize this dynamic area. This new angle contains sections on early human improvement, what constitutes human lifestyles, and what makes it detailed.

Additional assurance at the alterations among the biochemistry of prokaryotes and eukaryotes is usually integrated. the guts of lifestyles in prokaryotes is taken into account to be photosynthesis and sugar new release, whereas the guts of lifestyles in eukaryotes is sugar use and oxidative phosphorylation. This specified reference will tell really expert biochemistry classes and researchers of their figuring out of the function biochemistry has in human life.

  • Contextualizes the sphere of biochemistry and its function in human life
  • Includes devoted sections on human replica and human mind development
  • Provides broad assurance on biochemical energetics, oxidative phosphorylation, photosynthesis, and carbon monoxide-acetate pathways

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Biochemistry Labfax by Ali D. Hames, J. A.A. Chambers, D. Rickwood

By Ali D. Hames, J. A.A. Chambers, D. Rickwood

LABFAX volumes are purpose-designed info reference books for training scientists. every one publication offers key details for a big topic in a single position and so saves hours of looking. It doesn't easily gather jointly facts that are already on hand in catalogues when you consider that those are frequently incomplete and will include conflicting details. fairly, the authors and editors of every LABFAX quantity have searched the unique literature for the exact info which they recognize the professional needs.
Biochemistry LabFax is an in depth compendium of crucial details - on radioisotopes, enzymes, proteins, nucleic acids, lipids, plus information on chosen concepts corresponding to chromatography, electrophoresis, and so on. - wanted on a nearly day-by-day foundation through researchers in any quarter of biochemistry. additionally, the e-book acts as a gateway to different assets for info extra particular than will be lined in a quantity of this measurement

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Augustine's Confessions: Communicative Purpose and Audience by Annemare Kotze

By Annemare Kotze

This e-book is ready the communicative function and the viewers of the Confessions. It illuminates the measure to which the communicative function of the paintings is to transform its readers, i.e. a protreptic objective, and the measure to which the objective viewers should be pointed out as Augustine's capability Manichaean readers. a quick survey of attainable literary antecedents issues to the life of alternative works that encompass an analogous mix of an autobiographical part (a conversion tale) with a polemical and exegetical part (an argument that goals to persuade the reader of the benefits of a selected standpoint) that characterizes the Confessions. The ebook presents a brand new point of view at the which means and constitution of Augustine's frequently misunderstood masterpiece.

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